Cerebral venous sinus thrombosis in pregnancy: a case report
DOI:
https://doi.org/10.12809/hkjgom.20.2.06Keywords:
Headache, Pregnancy, Seizure, Sinus thrombosis, intracranialAbstract
We report a case of peripartum cerebral venous sinus thrombosis in a 33-year-old Chinese multiparous woman with 38 weeks of gestation and uneventful antenatal history who presented with a 3-day history of progressively worsening generalised headache. The woman later developed recurrent convulsions. After joint consultation with the neurologist, neurosurgeon, and anaesthetist, emergency Caesarean section under general anaesthesia was performed with perioperative anticonvulsant cover and postoperative anticoagulation therapy. A high index of clinical suspicion and multidisciplinary discussion are important for its timely management.
References
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Edlow AG, Edlow BL, Edlow JA. Diagnosis of acute neurologic emergencies in pregnant and postpartum women. Emerg Med Clin North Am 2016;34:943-65.
James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol 2005;106:509-16.
O’Neal MA. Headaches complicating pregnancy and the postpartum period. Pract Neurol 2017;17:191-202.
Li H, Cui L, Chen Z, Chen Y. Risk factors for early-onset seizures in patients with cerebral venous sinus thrombosis: a meta-analysis of observational studies. Seizure 2019;72:33-9.
Mortimer AM, Bradley MD, Likeman M, Stoodley NG, Renowden SA. Cranial neuroimaging in pregnancy and the post-partum period. Clin Radiol 2013;68:500-8.
Ferro JM, Bousser MG, Canhão P, et al. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology. Eur Stroke J 2017;2:195-221.
Lanska DJ, Kryscio RJ. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 2000;31:1274-82.
Edlow AG, Edlow BL, Edlow JA. Diagnosis of acute neurologic emergencies in pregnant and postpartum women. Emerg Med Clin North Am 2016;34:943-65.
James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol 2005;106:509-16.
O’Neal MA. Headaches complicating pregnancy and the postpartum period. Pract Neurol 2017;17:191-202.
Li H, Cui L, Chen Z, Chen Y. Risk factors for early-onset seizures in patients with cerebral venous sinus thrombosis: a meta-analysis of observational studies. Seizure 2019;72:33-9.
Mortimer AM, Bradley MD, Likeman M, Stoodley NG, Renowden SA. Cranial neuroimaging in pregnancy and the post-partum period. Clin Radiol 2013;68:500-8.
Ferro JM, Bousser MG, Canhão P, et al. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology. Eur Stroke J 2017;2:195-221.
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