Conservative management for placenta accreta spectrum disorders: experience of a regional hospital from 2013 to 2021

Authors

  • Yiu Fai Wong
  • Tsz Kin Lo
  • Viola Ying Tze Chan
  • Vivian Kwun Sin Ng
  • Wai Kuen Yung
  • Hin Hung Tsang
  • Chi Hung Koo
  • Danny Hing Yan Cho
  • Wai Lam Lau
  • Wing Cheong Leung

DOI:

https://doi.org/10.12809/hkjgom.23.2.342

Keywords:

Conservative treatment, Hysterectomy, Placenta, Placenta accreta, Postpartum haemorrhage

Abstract

Introduction: Conservative management by leaving the placenta in situ for placenta accreta spectrum (PAS) disorders can preserve the uterus with reduced surgical complications. This study aims to review the outcomes of planned conservative management for PAS disorders between January 2013 and December 2021.
Methods: The medical records of patients with clinically and/or histopathologically confirmed PAS disorders who underwent conservative management by leaving the placenta in situ between 1 January 2013 and 31 December 2021 at Kwong Wah Hospital, Hong Kong, were retrospectively reviewed. Uterine artery embolisation and various haemostatic methods were used to control bleeding.
Results: A total of 17 patients with PAS disorders were conservatively treated by leaving the placenta in situ. Of these, 15 patients had major placenta praevia; 16 patients had a history of Caesarean delivery; and 10 patients presented with sonographic features of PAS disorders. Intraoperatively, eight patients had partial placenta left in situ, whereas five patients had the entire placenta left in situ. All patients had good maternal outcomes and recovery, except for four patients who had major complications during the immediate postpartum period. Two patients eventually required a hysterectomy.
Conclusion: Planned conservative management for PAS disorders can achieve good clinical outcomes in a regional hospital with a multidisciplinary team.

References

Jauniaux E, Jurkovic D. Placenta accreta: pathogenesis of a 20th century iatrogenic uterine disease. Placenta 2012;33:244-51. DOI: https://doi.org/10.1016/j.placenta.2011.11.010

Cheng KK, Lee MM. Rising incidence of morbidly adherent placenta and its association with previous caesarean section: a 15-year analysis in a tertiary hospital in Hong Kong. Hong Kong Med J 2015;21:511-7. DOI: https://doi.org/10.12809/hkmj154599

Jauniaux E, Alfirevic Z, Bhide AG, et al. Placenta praevia and placenta accreta: diagnosis and management. Green-top Guideline No. 27a. BJOG 2019;126:e1-48.

Sentilhes L, Seco A, Azria E, et al. Conservative management or cesarean hysterectomy for placenta accreta spectrum: the PACCRETA prospective study. Am J Obstet Gynecol 2022;226:839.e1-24.

Sentilhes L, Kayem G, Chandraharan E, Palacios-Jaraquemada J, Jauniaux E; FIGO Placenta Accreta Diagnosis and Management Expert Consensus Panel. FIGO consensus guidelines on placenta accreta spectrum disorders: conservative management. Int J Gynaecol Obstet 2018;140:291-8. DOI: https://doi.org/10.1002/ijgo.12410

Lo TK, Yung WK, Lau WL, Law B, Lau S, Leung WC. Planned conservative management of placenta accreta - experience of a regional general hospital. J Matern Fetal Neonatal Med 2014;27:291-6. DOI: https://doi.org/10.3109/14767058.2013.818118

Jauniaux E, Bhide A, Kennedy A, et al. FIGO consensus guidelines on placenta accreta spectrum disorders: prenatal diagnosis and screening. Int J Gynaecol Obstet 2018;140:274-80. DOI: https://doi.org/10.1002/ijgo.12408

Kutuk MS, Ak M, Ozgun MT. Leaving the placenta in situ versus conservative and radical surgery in the treatment of placenta accreta spectrum disorders. Int J Gynaecol Obstet 2018;140:338-44. DOI: https://doi.org/10.1002/ijgo.12308

Huang KL, Leung-Chit Tsang L, Cheng YF, et al. Planned conservative management of placenta increta and percreta with prophylactic transcatheter arterial embolization and leaving placenta in situ for women who desire fertility preservation. Placenta 2020;97:51-7.

Schwickert A, van Beekhuizen HJ, Bertholdt C, et al. Association of peripartum management and high maternal blood loss at cesarean delivery for placenta accreta spectrum (PAS): a multinational database study. Acta Obstet Gynecol Scand 2021;100(Suppl 1):29-40.

Jauniaux E, Ayres-de-Campos D, Langhoff-Roos J, Fox KA, Collins S; FIGO Placenta Accreta Diagnosis and Management Expert Consensus Panel. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders. Int J Gynaecol Obstet 2019;146:20-4.

Ibrahim TH. Efficacy of tranexamic acid in reducing blood loss, blood and blood products requirements in cesarian sections for patients with placenta accreta. Ain-Shams J Anesthesiol 2019;11:31.

Sentilhes L, Sénat MV, Le Lous M, et al. Tranexamic acid for the prevention of blood loss after cesarean delivery. N Engl J Med 2021;384:1623-34.

Gizzo S, Patrelli TS, Gangi SD, et al. Which uterotonic is better to prevent the postpartum hemorrhage? Latest news in terms of clinical efficacy, side effects, and contraindications: a systematic review. Reprod Sci 2013;20:1011-9. DOI: https://doi.org/10.1177/1933719112468951

Meckstroth KR, Whitaker AK, Bertisch S, Goldberg AB, Darney PD. Misoprostol administered by epithelial routes: drug absorption and uterine response. Obstet Gynecol 2006;108:582-90. DOI: https://doi.org/10.1097/01.AOG.0000230398.32794.9d

D'Souza DL, Kingdom JC, Amsalem H, Beecroft JR, Windrim RC, Kachura JR. Conservative management of invasive placenta using combined prophylactic internal iliac artery balloon occlusion and immediate postoperative uterine artery embolization. Can Assoc Radiol J 2015;66:179-84. DOI: https://doi.org/10.1016/j.carj.2014.08.002

Downloads

Published

2023-06-02

How to Cite

1.
Wong YF, Lo TK, Chan VYT, Ng VKS, Yung WK, Tsang HH, Koo CH, Cho DHY, Lau WL, Leung WC. Conservative management for placenta accreta spectrum disorders: experience of a regional hospital from 2013 to 2021. Hong Kong J Gynaecol Obstet Midwifery [Internet]. 2023 Jun. 2 [cited 2024 Nov. 23];23(2). Available from: https://hkjgom.org/home/article/view/342

Issue

Section

Original Article

Most read articles by the same author(s)